|  |  |  |  | With anthracycline-based chemotherapy | No chemotherapy |  | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Alleles | MAF | Gene | Studya | HR | 95Â % CI | HR | 95Â % CI | p for interaction* | ||
rs733590 | A > G | 0.37 | CDKN1A | MARIE | 0.78 | 0.52 | 1.15 | 1.35 | 0.75 | 2.42 | 0.0781 |
 |  | 0.35 |  | BCAC | 1.30 | 0.87 | 1.96 | 1.11 | 0.94 | 1.31 | 0.4857 |
rs3135989 | A > C | 0.06 | LIG3 | MARIE | 1.67 | 0.87 | 3.20 | 0.84 | 0.26 | 2.72 | 0.0985 |
 |  | 0.07 |  | BCAC | 1.07 | 0.48 | 2.40 | 0.95 | 0.70 | 1.30 | 0.8537 |
rs140697 | G > A | 0.10 | MBD4 | MARIE | 0.39 | 0.15 | 0.99 | 0.89 | 0.39 | 2.07 | 0.0868 |
 |  | 0.09 |  | BCAC | 0.93 | 0.42 | 2.07 | 0.84 | 0.62 | 1.15 | 0.9496 |
rs2005618 | A > G | 0.10 | MBD4 | MARIE | 0.39 | 0.15 | 0.99 | 0.89 | 0.39 | 2.07 | 0.0868 |
 |  | 0.09 |  | BCAC | 0.93 | 0.42 | 2.07 | 0.84 | 0.62 | 1.15 | 0.9563 |
rs1052133 | C > G | 0.22 | OGG1 | MARIE | 1.25 | 0.85 | 1.83 | 0.63 | 0.29 | 1.37 | 0.0687 |
 |  | 0.22 |  | BCAC | 0.94 | 0.55 | 1.61 | 0.93 | 0.76 | 1.14 | 0.9496 |
rs2269112 | G > A | 0.16 | OGG1 | MARIE | 1.43 | 0.93 | 2.20 | 0.71 | 0.38 | 1.32 | 0.0976 |
 |  | 0.15 |  | BCAC | 1.14 | 0.58 | 2.22 | 1.03 | 0.82 | 1.30 | 0.8395 |
rs878156 | A > G | 0.07 | PARP2 | MARIE | 0.82 | 0.41 | 1.66 | 2.78 | 1.15 | 6.73 | 0.0549 |
 |  | 0.07 |  | BCAC | 0.55 | 0.18 | 1.64 | 1.32 | 1.00 | 1.75 | 0.0361 |
rs3136717 | A > G | 0.10 | POLB | MARIE | 1.42 | 0.80 | 2.53 | 0.19 | 0.05 | 0.78 | 0.0218 |
 |  | 0.12 |  | BCAC | 0.45 | 0.20 | 1.02 | 0.94 | 0.74 | 1.20 | 0.0883 |
rs3136781 | A > C | 0.10 | POLB | MARIE | 1.45 | 0.81 | 2.58 | 0.19 | 0.05 | 0.78 | 0.0173 |
 |  | 0.11 |  | BCAC | 0.45 | 0.20 | 1.02 | 0.94 | 0.74 | 1.20 | 0.0909 |
rs3136790 | A > C | 0.10 | POLB | MARIE | 1.45 | 0.81 | 2.58 | 0.19 | 0.05 | 0.78 | 0.0191 |
 |  | 0.12 |  | BCAC | 0.45 | 0.20 | 1.02 | 0.94 | 0.74 | 1.20 | 0.0883 |
rs2233921 | C > A | 0.45 | SMUG1 | MARIE | 1.31 | 0.92 | 1.88 | 0.71 | 0.38 | 1.32 | 0.0156 |
 |  | 0.49 |  | BCAC | 0.71 | 0.47 | 1.08 | 0.90 | 0.77 | 1.06 | 0.5463 |
rs3213255 | A > G | 0.43 | XRCC1 | MARIE | 0.77 | 0.53 | 1.12 | 1.48 | 0.82 | 2.69 | 0.0712 |
 |  | 0.42 |  | BCAC | 1.33 | 0.86 | 2.04 | 0.90 | 0.76 | 1.06 | 0.1734 |
rs3213356 | A > G | 0.44 | XRCC1 | MARIE | 0.73 | 0.50 | 1.07 | 1.74 | 0.95 | 3.18 | 0.0267 |
 |  | 0.44 |  | BCAC | 1.20 | 0.78 | 1.84 | 0.89 | 0.75 | 1.04 | 0.2947 |