Fig. 3

Meta-analysis of XRCC1 rs3213356 and breast cancer prognosis according to chemotherapy. Forest plot of meta-analysis of hazard ratios and 95 % confidence intervals for XRCC1 rs3213356 in the discovery MARIE study and the replication in Breast Cancer Association Consortium (BCAC) using fixed effect model, according to treatment, i.e. no chemotherapy (a), any type of chemotherapy (b) and anthracycline-based chemotherapy . The associations for the BCAC studies were based on pooled analysis stratified by study and adjusted for covariables (see Methods)