TY - JOUR AU - Robinson, Cleo AU - Dick, Ian M. AU - Wise, Michael J. AU - Holloway, Andrew AU - Diyagama, Dileepa AU - Robinson, Bruce W. S. AU - Creaney, Jenette AU - Lake, Richard A. PY - 2015 DA - 2015/12/18 TI - Consistent gene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma JO - BMC Cancer SP - 983 VL - 15 IS - 1 AB - The MexTAg transgenic mouse model of mesothelioma replicates many aspects of human mesothelioma, including induction by asbestos, pathogenicity and response to cytotoxic chemotherapy, despite high levels of the SV40 large T Antigen (TAg) in the mesothelial compartment. This model enables analysis of the molecular events associated with asbestos induced mesothelioma and is utilised here to investigate the molecular dynamics of tumours induced in these mice, using gene expression patterns as a read out. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-015-1953-y DO - 10.1186/s12885-015-1953-y ID - Robinson2015 ER -