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Fig. 3 | BMC Cancer

Fig. 3

From: CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma

Fig. 3

Effect of CYP1B1 knockdown on apoptosis. Apoptosis assays with Caki-1 (a) and 769-P (b) cells were done 48 h post siRNA transfection. Representative biparametric histogram showing cell population in early (bottom right quadrant) and late (top right quadrant) apoptotic and viable (bottom left quadrant) states. The bar chart indicates the ratio of apoptotic cell fractions (early plus apoptotic cells) in CYP1B1 transfectants compared with controls. Apoptotic cell fractions are expressed as relative value composed to the average expression of control siRNA transfectant. *, P < 0.05

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