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Fig. 1 | BMC Cancer

Fig. 1

From: CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma

Fig. 1

CYP1B1 expression in RCC cell lines and tissues. a Representative immunoblot displaying CYP1B1 expression in normal kidney (NK) sample, Caki-1, Caki-2, A498, ACHN, 786-O and 769-P. CYP1B1 protein was up-regulated in RCC cell lines in comparison with that of NK. b Representative immunostaining of CYP1B1 in clinical sample obtained from tissue microarray. (a) Weak cytoplastic staining of CYP1B1 was observed in the normal renal tubules. (b) Strong cytoplasmic staining of CYP1B1 was observed in clear cell RCC tumors. (c) CYP1B1 overexpression was also observed in chromophobe RCC tumors. (d) CYP1B1 staining score in clinical samples. CYP1B1 protein expression in RCC samples was significantly higher than that of normal kidney tissues . **, P < 0.01

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