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Table 2 The results from ROCK phosphorylation staining, stratified by tumor types

From: Immunohistochemical evaluation of ROCK activation in invasive breast cancer

Tumor type Cytoplasmic staining Nuclear staining
Negative/weak Moderate Strong P a Mean %
(Standard deviation)
P b
ROCKII S1366 phosphorylation
 CIS 52 (93 %) 4 (7 %) 0 (0 %) ] 0.886
] 0.814
6.9 (16.4) ] 0.329 ] 0.003
 IC 107 (92 %) 9 (8 %) 0 (0 %) 8.7 (20.7)
 ICM 91 (88 %) 12 (12 %) 0 (0 %) 20.8 (29.6)
ROCKI S1333 phosphorylation
 CIS 50 (89 %) 5 (9 %) 1 (2 %) ] 0.433
] 0.450
1.3 (5.1) ] 0.908
] 0.933
 IC 96 (83 %) 19 (17 %) 0 (0 %) 0.9 (3.8)
 ICM 86 (83 %) 16 (16 %) 1 (1 %) 2.1 (8.4)
  1. Data presented as number (%) for cytoplasmic staining and mean % (Standard deviation) for nuclear staining. Bold values indicate statistical significance (P < 0.05)
  2. CIS, Carcinoma in situ; IC, Invasive carcinoma; ICM, Invasive carcinoma with metastasis. aChi-square test for trend. bMann-Whitney test