Table 3 Univariate and multivariate analysis of the association between demographic and cancer characteristics and treatment by chemotherapy
From: Under-treatment of elderly patients with ovarian cancer: a population based study
Chemotherapy (N = 794) | No chemotherapy (N = 357) | p | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|---|---|
N | % | N | % | OR (95 % CI) | ORa (95 % CI) | |||
Age | ≤70 | 537 | 76.4 % | 166 | 23.6 % | <0.0001 | 1 | 1 |
>70 | 257 | 57.4 % | 191 | 42.6 % | 0.42 (0.32–0.54) | 0.34 (0.24–0.48) | ||
Stage | ||||||||
I-II | 147 | 49.5 % | 150 | 50.5 % | <0.0001 | 0.36 (0.25–0.52) | 0.13 (0.08–0.21) | |
III | 459 | 82.7 % | 96 | 17.3 % | 1.77 (1.23–2.54) | 1.28 (0.83–1.97) | ||
IV | 173 | 73.0 % | 64 | 27.0 % | 1 | 1 | ||
15 | 24.2 % | 47 | 75.8 % | 0.12 (0.06–0.23) | 0.14 (0.06–0.32) | |||
Adjuvant treatment | yes | 677 | 74.2 % | 235 | 25.8 % | 3.03 (2.22–4) | 2.60 (1.67–4.05) | |
no | 117 | 49.0 % | 122 | 51.0 % | <0.0001 | 1 | 1 | |
Histology | <0.0001 | |||||||
Epithelial | 765 | 74.0 % | 269 | 26.0 % | 1 | 1 | ||
Other | 17 | 36.2 % | 30 | 63.8 % | 0.20 (0.11–0.37) | 0.37 (0.18–0.76) | ||
No histology | 12 | 17.1 % | 58 | 82.9 % | 0.07 (0.04–0.14) | 0.23 (0.11–0.48) | ||
Grade | <0.0001 | |||||||
1 | 48 | 59.3 % | 33 | 40.7 % | 1 | 1 | ||
2 | 144 | 79.6 % | 37 | 20.4 % | 2.68 (1.51–4.74) | 2.01 (1.04–3.89) | ||
3 | 197 | 86.0 % | 32 | 14.0 % | 4.23 (2.37–7.56) | 2.85 (1.48–5.50) | ||
Unkown | 405 | 61.4 % | 255 | 38.6 % | 1.09 (0.68–1.75) | 1.31 (0.75–2.27) | ||
Treatment location | ||||||||
Private | 467 | 71.7 % | 184 | 28.3 % | <0.0001 | 0.91 (0.68–1.22) | 1.15 (0.81–1.63) | |
Public Univ. | 265 | 73.6 % | 95 | 26.4 % | 1 | 1 | ||
Public non-Univ. | 40 | 47.6 % | 44 | 52.4 % | 0.33 (0.20–0.53) | 0.41 (0.23–0.75) | ||
Unkown | 22 | 39.3 % | 34 | 60.7 % | 0.23 (0.13–0.42) | 0.37 (0.17–0.78) | ||
Period of diagnosis | ||||||||
≤2002 | 298 | 67.3 % | 145 | 32.7 % | 0.1637 | 1 | 1 | |
2003–2007 | 265 | 73.0 % | 98 | 27.0 % | 1.30 (0.96–1.77) | 1.78 (1.23–2.57) | ||
≥2008 | 231 | 67.2 % | 113 | 32.8 % | 0.99 (0.74–1.34) | 1.26 (0.87–1.83) | ||
Area of residence | ||||||||
Rural | 115 | 69.3 % | 51 | 30.7 % | 0.9297 | |||
Urban | 679 | 68.9 % | 306 | 31.1 % | ||||