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Table 4 Univariate and multivariate analyses predicting LNM using preoperative values

From: Difficulty of predicting the presence of lymph node metastases in patients with clinical early stage gastric cancer: a case control study

Variable Univariate Multivariate
OR (95 % CI) p-value OR (95 % CI) p-value
Gender Male 1 0.118   
  Female 1.46 (0.91–2.34)    
Agea   0.98 (0.96–0.99) 0.025 0.98 (0.96–0.99) 0.017
BMIa   1.00 (0.93–1.08) 0.977   
Gross type 0-I, IIa 1 0.585   
  IIb 0.70 (0.35–1.39) 0.304   
  IIc, III 0.86 (0.50–1.45) 0.563   
Histology Pap, WD, MD 1 0.515   
  PD, Muc 1.36 (0.76–2.43) 0.300   
  Sig 1.00 (0.57–1.76) 0.991   
Ulcer Negative 1 0.037 1 0.037
  Positive 2.21 (1.05–4.67)   2.25 (1.05–4.81)  
Location Upper third 1 0.893   
  Lower or middle third 1.05 (0.54–2.09)    
Tumor sizea   1.04 (1.01–1.07) 0.010 1.04 (1.01–1.07) 0.009
NLRa   1.08 (0.95–1.22) 0.228   
Tumor detectability in CT scan Undetectable 1 0.355   
Detectable 1.30 (0.75–2.26)    
Presence of LMN in CT scan Unsuspected 1 0.001 1 0.002
Suspected 3.92 (1.80–8.55)   3.57 (1.62–7.88)  
  1. aAnalyses were performed using continuous values
  2. LNM lymph node metastasis, OR odds ratio, CI confidence interval, BMI body-mass index, Pap papillary adenocarcinoma, WD well differentiated adenocarcinoma, MD moderately differentiated adenocarcinoma, Muc mucinous adenocarcinoma, PD poorly differentiated adenocarcinoma, Sig signet cell ring carcinoma, CLS carcinoma with lymphoid stroma, NLR neutrophil-lymphocyte ratio, CT computed tomography