|
Variable
|
Univariate
|
Multivariate
|
|---|
|
OR (95 % CI)
|
p-value
|
OR (95 % CI)
|
p-value
|
|---|
|
Gender
|
Male
|
1
|
0.118
| | |
| |
Female
|
1.46 (0.91–2.34)
| | | |
|
Agea
| |
0.98 (0.96–0.99)
|
0.025
|
0.98 (0.96–0.99)
|
0.017
|
|
BMIa
| |
1.00 (0.93–1.08)
|
0.977
| | |
|
Gross type
|
0-I, IIa
|
1
|
0.585
| | |
| |
IIb
|
0.70 (0.35–1.39)
|
0.304
| | |
| |
IIc, III
|
0.86 (0.50–1.45)
|
0.563
| | |
|
Histology
|
Pap, WD, MD
|
1
|
0.515
| | |
| |
PD, Muc
|
1.36 (0.76–2.43)
|
0.300
| | |
| |
Sig
|
1.00 (0.57–1.76)
|
0.991
| | |
|
Ulcer
|
Negative
|
1
|
0.037
|
1
|
0.037
|
| |
Positive
|
2.21 (1.05–4.67)
| |
2.25 (1.05–4.81)
| |
|
Location
|
Upper third
|
1
|
0.893
| | |
| |
Lower or middle third
|
1.05 (0.54–2.09)
| | | |
|
Tumor sizea
| |
1.04 (1.01–1.07)
|
0.010
|
1.04 (1.01–1.07)
|
0.009
|
|
NLRa
| |
1.08 (0.95–1.22)
|
0.228
| | |
|
Tumor detectability in CT scan
|
Undetectable
|
1
|
0.355
| | |
|
Detectable
|
1.30 (0.75–2.26)
| | | |
|
Presence of LMN in CT scan
|
Unsuspected
|
1
|
0.001
|
1
|
0.002
|
|
Suspected
|
3.92 (1.80–8.55)
| |
3.57 (1.62–7.88)
| |
-
aAnalyses were performed using continuous values
-
LNM lymph node metastasis, OR odds ratio, CI confidence interval, BMI body-mass index, Pap papillary adenocarcinoma, WD well differentiated adenocarcinoma, MD moderately differentiated adenocarcinoma, Muc mucinous adenocarcinoma, PD poorly differentiated adenocarcinoma, Sig signet cell ring carcinoma, CLS carcinoma with lymphoid stroma, NLR neutrophil-lymphocyte ratio, CT computed tomography
