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Table 1 Pharmacokinetic parameters of the analyzed patient and reported data of patients with normal kidney function

From: Pharmacokinetics and safety of cyclophosphamide and docetaxel in a hemodialysis patient with early stage breast cancer: a case report

Compound Unit Patient Reference Deviation (%)
Cyclophosphamide     
Cmax μg/mL 48.97 61.32 21.2 %
t1/2 hour 66.96 4 ~ 6 1016 %
AUC0~∞ μg · h/mL 3128 1917 56 %
Docetaxel     
Cmax ng/mL 1132.6 1309 ~ 2930 13.6 ~ 61.4 %
t1/2 hour 21.53 7.8 ~ 21.0 2.5 ~ 176 %
AUC0~∞ ng · h/mL 4430 1990 ~ 3770 17 ~ 122 %