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Table 2 Overall and subgroups analyses of GSTP1 methylation and breast cancer risk

From: Aberrant GSTP1 promoter methylation is associated with increased risk and advanced stage of breast cancer: a meta-analysis of 19 case-control studies

Study groups Number OR (95 % CI) Heterogeneity
Ph I2 (%) χ2
Overall 19 7.85 (5.12, 12.01) 0.20 21 22.69
Ethnicity
 Caucasians 10 7.23 (3.76, 13.90) 0.67 0 6.65
 Asians 7 11.71 (5.69, 24.07) 0.61 0 4.53
Sample type
 Tissue 14 10.32 (5.97, 17.85) 0.58 0 11.39
 Blood 5 4.02 (1.12, 14.38) 0.07 54 8.64
Method
 Quantitative 8 4.73 (1.84, 12.12) 0.08 45 12.84
 Semi-quantitative 4 10.33 (3.32, 32.10) 0.86 0 0.77
 Non-quantitative 7 12.55 (5.72, 27.55) 0.61 0 4.51
  1. N number of trials, OR odds ratio