Fig. 5
From: AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas
Stable AXL knockdown in Lipo-246 cells significantly reduces tumor weight and volume. a AXL knockdown in Lipo-246 cells was evaluated by western blot prior to subcutaneous injection. b Tumor volume was monitored at the indicated time points. c Xenografts were weighed ex vivo following experiment termination. d Representative IHC images of Lipo-246 xenografts expressing NT control constructs or one of two AXL-targeting shRNAs are shown (400× magnification). Hematoxylin-eosin (H&E); cleaved caspase 3 (CC3). (* = p < 0.05; *** = p < 0.001)