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Fig. 3 | BMC Cancer

Fig. 3

From: AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas

Fig. 3

Transient knockdown of AXL decreases cell proliferation, migration, and invasion. a Representative western blots showing signaling dysregulation in Lipo-246, Lipo-863, LiSa2, and PLS-1 cells that were transfected with either NT or AXL-specific siRNA. b Cell proliferation of AXL-specific siRNA-transfected DDLPS and PLS cell lines was measured by MTS assay after 48 h (96 h post-transfection). Percent of cell growth is expressed as a percentage of control. c Modified Boyden chambers were used to assess DDLPS and PLS cell migration and invasion following transfection with AXL-targeting siRNA. Percent of cell migration and invasion is expressed as a percentage of control. The data in the bar graphs are means with SEMs for triplicate experiments (* = p < 0.05; *** = p < 0.001)

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