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Table 3 Cox univariate and multivariate regression analysis for OS in 125 ER+ patients

From: Using second harmonic generation to predict patient outcome in solid tumors

  Univariate analysis Multivariate analysisa
Variable HR 95 % CI p HR 95 % CI p
Age       
 41–55 vs 40 years 0.49 0.21–1.17 0.108 0.61 0.25–1.52 0.289
 56–70 vs 40 years 0.57 0.24–1.35 0.204 0.29 0.09–0.95 0.041
  > 70 vs 40 years 0.33 0.09–1.26 0.105 0.20 0.04–0.95 0.043
Menopausal status       
 Post- vs premenopausal 1.14 0.61–2.11 0.686 2.90 0.99–8.49 0.052
Tumor size       
 2–5 vs ≤2 cm 1.25 0.66–2.37 0.494 0.56 0.26–1.20 0.137
  > 5 vs ≤2 cm 1.66 0.39–7.11 0.492 0.75 0.15–3.72 0.720
Tumor grade       
 II vs I 2.53 1.02–6.24 0.044 2.16 0.84–5.55 0.111
 III vs I 5.02 1.89–13.36 0.001 4.88 1.64–14.56 0.004
PgR status       
 Positive vs negative 0.51 0.26–1.01 0.055 0.48 0.23–1.01 0.054
HER2 status       
 Positive vs negative 3.15 1.11–8.96 0.031 3.80 1.18–12.20 0.025
Log of F/B ratio 0.34 0.11–1.03 0.005 0.29 0.07–1.10 0.068
  1. aThe multivariate model included 123 patients due to 2 missing values for tumor grade