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Table 2 Hazard ratios (HRs) of NPC deaths by smoking status in the combined cohort (both sexes)

From: Smoking and nasopharyngeal carcinoma mortality: a cohort study of 101,823 adults in Guangzhou, China

  Total person-years of participants Mortality rate of NPC per 10,000 person-years (95 % CI) Crude HR (95 % CI) Model 1 HR (95 % CI)
Never smokers 409,095 0.22 (0.11–0.42) 1.00 1.00
Smoking status
 Daily smokers 337,064 0.74 (0.50–1.10) 3.57 (1.66–7.65)** 2.95 (1.01–8.68)*
Smoking amount (cigarettes/day)
 1–14 162,244 0.49 (0.25–0.99) 2.45 (0.94–6.37) 1.74 (0.45–6.79)
 15+ 174,820 0.97 (0.60–1.56) 4.52 (2.01–10.14)** 4.00 (1.29–12.35)*
 P for trend    <0.001 0.012
Smoking duration (years)
 1–9 87,556 0.46 (0.17–1.22) 2.36 (0.72–7.73) 3.07 (0.69–13.62)
 10+ 249,508 0.84 (0.55–1.29) 3.94 (1.80–8.60)** 2.93 (0.97–8.89)
 P for trend    0.001 0.064
Smoking cumulative consumption (pack-years)
  < 10 181,243 0.33 (0.15–0.74) 1.65 (0.59–4.66) 1.76 (0.45–6.89)
 10+ 155,821 1.22 (0.78–1.91) 5.52 (2.50–12.20)** 4.03 (1.29–12.58)*
 P for trend    <0.001 0.014
  1. Model 1- adjusted by age, sex, education, drinking status, cohort status & occupation (including cadre level workers, general workers, and drivers), accounted for smoking-drinking interaction
  2. *p < 0.05, **p < 0.01