Skip to main content

Table 3 Association between irisin levels and breast tumor characteristics

From: Serum irisin levels are lower in patients with breast cancer: association with disease diagnosis and tumor characteristics

Characteristics

N (%)

Irisin levels (μg/ml)

p-value

Tumor size (cm)

  

0.084

≤2.0

43 (48.3 %)

2.34 ± 0.52

 

2.1–5.0

31 (34.8 %)

2.58 ± 0.59

 

>5.0

15 (16.9 %)

2.65 ± 0.57

 

Grade

  

0.450

I

14 (14.3 %)

2.35 ± 0.59

 

II

29 (29.6 %)

2.42 ± 0.59

 

III

55 (56.1 %)

2.54 ± 0.56

 

Stage

  

0.039

I

21 (30.4 %)

2.31 ± 0.54

 

II

28 (40.6 %)

2.52 ± 0.58

 

III

20 (29.0 %)

2.75 ± 0.50a

 

Lymph nodes

  

0.098

Negative

40 (56.3 %)

2.44 ± 0.58

 

Positive

31 (43.7 %)

2.66 ± 0.53

 

Concurrent DCIS

  

0.161

No

34 (34.0 %)

2.37 ± 0.58

 

Yes

66 (66.0 %)

2.54 ± 0.56

 

ER status

  

0.966

Negative

24 (25.3 %)

2.46 ± 0.58

 

Positive

71 (74.7 %)

2.46 ± 0.56

 

PR status

  

0.904

Negative

30 (29.7 %)

2.47 ± 0.57

 

Positive

65 (68.4 %)

2.46 ± 0.57

 

c-erb-B2 status

  

0.226

Negative

64 (68.1 %)

2.41 ± 0.52

 

Positive

30 (31.9 %)

2.56 ± 0.66

 

Ki67 Value

  

0.243

<10 %

23 (24.5 %)

2.27 ± 0.54

 

10–15 %

16 (17.0 %)

2.53 ± 0.67

 

16–30 %

25 (26.6 %)

2.58 ± 0.54

 

>30 %

30 (31.9 %)

2.49 ± 0.53

 

P53 status

  

0.759

<10 %

52 (57.8 %)

2.45 ± 0.55

 

>10 %

38 (42.2 %)

2.49 ± 0.57

 
  1. Data are presented as mean ± standard deviation
  2. acompared to stage I after Bonferroni correction for multiple comparisons