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Table 3 Association between irisin levels and breast tumor characteristics

From: Serum irisin levels are lower in patients with breast cancer: association with disease diagnosis and tumor characteristics

Characteristics N (%) Irisin levels (μg/ml) p-value
Tumor size (cm)    0.084
≤2.0 43 (48.3 %) 2.34 ± 0.52  
2.1–5.0 31 (34.8 %) 2.58 ± 0.59  
>5.0 15 (16.9 %) 2.65 ± 0.57  
Grade    0.450
I 14 (14.3 %) 2.35 ± 0.59  
II 29 (29.6 %) 2.42 ± 0.59  
III 55 (56.1 %) 2.54 ± 0.56  
Stage    0.039
I 21 (30.4 %) 2.31 ± 0.54  
II 28 (40.6 %) 2.52 ± 0.58  
III 20 (29.0 %) 2.75 ± 0.50a  
Lymph nodes    0.098
Negative 40 (56.3 %) 2.44 ± 0.58  
Positive 31 (43.7 %) 2.66 ± 0.53  
Concurrent DCIS    0.161
No 34 (34.0 %) 2.37 ± 0.58  
Yes 66 (66.0 %) 2.54 ± 0.56  
ER status    0.966
Negative 24 (25.3 %) 2.46 ± 0.58  
Positive 71 (74.7 %) 2.46 ± 0.56  
PR status    0.904
Negative 30 (29.7 %) 2.47 ± 0.57  
Positive 65 (68.4 %) 2.46 ± 0.57  
c-erb-B2 status    0.226
Negative 64 (68.1 %) 2.41 ± 0.52  
Positive 30 (31.9 %) 2.56 ± 0.66  
Ki67 Value    0.243
<10 % 23 (24.5 %) 2.27 ± 0.54  
10–15 % 16 (17.0 %) 2.53 ± 0.67  
16–30 % 25 (26.6 %) 2.58 ± 0.54  
>30 % 30 (31.9 %) 2.49 ± 0.53  
P53 status    0.759
<10 % 52 (57.8 %) 2.45 ± 0.55  
>10 % 38 (42.2 %) 2.49 ± 0.57  
  1. Data are presented as mean ± standard deviation
  2. acompared to stage I after Bonferroni correction for multiple comparisons