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Table 2 Alcohol intake and risk of breast cancer by hormone receptor status in the Swedish Women’s Lifestyle and Health study

From: Alcohol consumption, body mass index and breast cancer risk by hormone receptor status: Women’ Lifestyle and Health Study

Alcohol intake (g/day) Total 0 0.1–5 5.1–15 >15 Per 5 g/day increase
No. of participants 45,233 10,153 22,249 11,734 1,097  
Person-year 758,430 151,813 354,589 221,531 30,497  
Total breast cancer (No.) 1,385 276 646 421 42  
RR (95 % CI)- unadjusted   1.0 1.07 (0.92–1.25) 1.24 (1.06–1.45) 1.29 (0.99–1.67) 1.02 (1.00–1.04)
RR (95 % CI)- adjusted   1.0 1.03 (0.89–1.20) 1.16 (0.99–1.36) 1.17 (0.90–1.53) 1.01 (0.98–1.04)
ER(+)/PR(+) breast cancer (No.) 718 140 353 205 19  
RR (95 % CI)- unadjusted   1.0 1.17 (0.95–1.46) 1.25 (1.00–1.56) 1.21 (0.83–1.77) 1.02 (0.98–1.05)
RR (95 % CI)- adjusted   1.0 1.13 (0.91–1.40) 1.17 (0.93–1.47) 1.11 (0.76–1.63) 1.01 (0.97–1.05)
ER(+)/PR(−) breast cancer (No.) 196 39 88 65 4  
RR (95 % CI)- unadjusted   1.0 0.99 (0.66–1.50) 1.31 (0.87–1.99) 1.04 (0.51–2.15) 1.01 (0.95–1.08)
RR (95 % CI)- adjusted   1.0 1.00 (0.66–1.51) 1.35 (0.89–2.06) 1.09 (0.53–2.25) 1.02 (0.95–1.08)
ER(−)/PR(−) breast cancer (No.) 187 45 83 51 8  
RR (95 % CI)- unadjusted   1.0 0.95 (0.64–1.42) 1.03 (0.67–1.57) 1.27 (0.64–2.52) 1.01 (0.92–1.10)
RR (95 % CI)- adjusted   1.0 0.90 (0.60–1.33) 0.91 (0.59–1.39) 1.04 (0.52–2.08) 0.98 (0.87–1.33)
  1. Adjusted models were adjusted for educational attainment (0–11 years/>11 years), history of breast cancer in mother and/or sister (Yes/No), smoking habits (current/former/never smokers), age at menarche (years), parity at baseline (0, 1, 2, 3, and >3), age at the first child birth (years), total breast feeding duration (months), and oral contraceptive use (current/former/never)
  2. RR relative risk, CI confidence interval, ER estrogen receptor, PR progesterone receptor