Table 1 Population characteristics

Male

19

66 %

Female

10

33 %

Age at diagnosis

18,1

median (min-max)

19

8 – 65

Age at initiation of treatment

19

median (min-max)

20

9 – 72

≤18 years

15

45 %

Histological subtype of osteosarcoma

osteoblastic

18

62 %

chondroblastic

5

17 %

osteogenic

3

10 %

telangiectasic

2

7 %

pleiomorphic

1

4 %

Tumor grade

Grade III

29

100 %

Stage at beginning of TT

progression

30

91 %

complete remission after relapse

3

9 %

Localization of relapse

localized

0

0 %

metastatic

24

73 %

both

9

27 %

Number of previous treatment lines

2,9

median (min-max)

3

1 – 8

0

0

0 %

1

4

12 %

2

12

36 %

3

10

30 %

≥4

7

21 %

Delay diagnosis - initiation of TT

2,8 years

median (min-max)

2,7 years

(0,6 – 7 years)