Group | TFN | MTF | MR (%) | TV (ml) | TW (g) | IR (%) |
---|
Blank | 7 (7/7) | 103 ± 26.40 | 100 | 1.40 ± 0.64 | 1.77 ± 0.44 | _ |
Control | 7 (7/7) | 94.86 ± 30.62 | 100 | 1.32 ± 0.75 | 1.67 ± 0.37 | 5.65 |
Peptide 1
| 7 (5/7) | 28.60 ± 13.16*
| 71.4*
| 0.24 ± 0.18#
| 0.52 ± 0.28* | 70.62 |
-
TFN tumor formation number, MTF metastatic tumor foci, MR metastatic rate, TV tumor volume, TW tumor weight, IR inhibitory rate; The values of metastatic tumor foci and tumor weight are presented as mean ± SD of n = 7 mice in relevant groups. *P < 0.001 and #
p < 0.05 vs. the control and HO8910 groups
-
TFN, Five weeks post-inoculation, the nude mice were sacrificed, and then tumor formation was calculated for each mouse
-
MTF, collection of all tumors in each mouse, and then measurements of the number of tumors
-
MR, the MR of control = the MIF of control/ the MIF of blank; the MR of Peptide 1 = the MIF of Peptide 1 /the MIF of blank;
-
TW, collect all the tumors from each mouse, and then their weights by scale
-
IR, IR of control = [1-(the weight of control/the weight of blank)] *100 %
- IR of Peptide 1 = [1-(the weight of Peptide 1/the weight of blank)] *100 %