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Fig. 5 | BMC Cancer

Fig. 5

From: A prospective study on histone γ-H2AX and 53BP1 foci expression in rectal carcinoma patients: correlation with radiation therapy-induced outcome

Fig. 5

Correlation between the γ-H2AX foci expression and tumor staging (II, III, IV). Peripheral lymphocytes were prepared from the blood samples derived from RC patients. a Foci counting for γ-H2AX was performed in non-irradiated, b irradiated in vitro with 0.5 and c 2 Gy samples 30 min and 24 h post-IR or d after 5 clinical fractions. Filled squares represent the mean values (± SE) for the respective group. Locoregional tumor stage was evaluated according to the standard UICC criteria (endoscopy, endorectal ultrasound and MRI) which gave 11, 35, and 7 cases (Additional file 1: Tables S1 and S2, pre-RT) scored as stage II, III, and IV, respectively. “n.s.” indicates that the difference was not highly significant (p > 0.05)

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