Colon | Rectum | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Liver | Lung | Distant LN | Liver | Lung | Distant LN | |||||||
P | P | P | P | P | P | |||||||
Factor | Uni | Multi | Uni | Multi | Uni | Multi | Uni | Multi | Uni | Multi | Uni | Multi |
Age (years): ≥70 | 0.55 | – | 0.20 | – | 0.054 | 0.15 | 0.057 | – | 0.74 | – | 0.64 | – |
Gender: Male | 0.27 | – | 0.10 | – | 0.025 | 0.041 | 0.41 | – | 0.94 | – | 0.70 | – |
CEA (ng/ml): >5 | 0.14 | – | 0.26 | – | 0.54 | – | 0.78 | – | 0.59 | – | 0.75 | – |
pT: 4 | 0.016 | 0.88 | 0.51 | – | 0.0097 | 0.76 | 0.65 | – | 0.93 | – | 0.092 | 0.32 |
Tumor size (cm): <5 | 0.88 | – | 0.58 | – | 0.60 | – | 0.099 | – | 0.02 | 0.14 | 0.11 | – |
Histology: well/moderate | 0.46 | – | 0.29 | – | 0.72 | – | 0.63 | – | 0.75 | – | 0.51 | – |
pN: (+) | 0.0003 | 0.70 | 0.057 | 0.51 | 0.0006 | 0.64 | 0.023 | 0.22 | 0.0003 | 0.078 | 0.0097 | 0.55 |
Total LNs count: <12 | 0.41 | – | 0.17 | – | 0.43 | – | 0.099 | – | 0.064 | 0.16 | 0.36 | – |
LN ratio: ≥0.29 | 0.0013 | 0.99 | 0.098 | 0.49 | 0.0002 | 0.92 | 0.076 | – | <0.0001 | 0.20 | 0.0041 | 0.44 |
Lymphatic invasion: (+) | 0.033 | 0.37 | 0.50 | – | 0.28 | – | 0.13 | – | 0.023 | 0.48 | 0.015 | 0.13 |
Venous invasion: (+) | 0.029 | 0.37 | 0.090 | 0.18 | 0.065 | 0.49 | 0.84 | – | 0.28 | – | 0.066 | 0,28 |
Chemotherapy: (−) | 0.11 | – | 0.46 | – | 0.0003 | 0.18 | 0.82 | – | 0.30 | – | 0.083 | 0.29 |
iTD: (+) | <0.0001 | 0.013 | 0.80 | – | <0.0001 | 0.0055 | 0.011 | 0.0032 | 0.0008 | 0.27 | 0.029 | 0.59 |
nTD: (+) | <0.0001 | 0.010 | 0.50 | – | 0.0026 | 0.15 | 0.70 | – | 0.12 | – | 0.94 | – |
ECLNI: (+) | 0.0004 | 0.22 | 0.04 | 0.27 | <0.0001 | 0.078 | 0.027 | 0.20 | 0.03 | 0.45 | 0.022 | 0.16 |