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Table 1 Association between SOX4 expression and clinicopathological parameters in patients with oral squamous cell carcinoma

From: SOX4 expression is associated with treatment failure and chemoradioresistance in oral squamous cell carcinoma

Parameters   SOX4 expression p-value
Total (n = 85) Low (n = 41) High (n = 44)
Age (yr)     0.161
 <64 41 23 18  
 ≥64 44 18 26  
Sex     0.492
 Male 61 28 33  
 Female 24 13 11  
Location     0.654
 Oral tongue 60 28 32  
 FOM, BM, RMT 25 13 12  
Stage     0.651
 I, II 56 28 28  
 III, IV 29 13 16  
T stage     0.843
 T1, T2 74 36 38  
 T3, T4 11 5 6  
N stage     0.327
 N0 60 31 29  
 N1, N2 25 10 15  
CRT     0.622
 No 35 23 27  
 Yes 50 18 17  
Recurrence     0.004
 No 53 32 21  
 Yes 32 9 23  
Treatment failure     0.032
 No 59 33 26  
 Yes 26 8 18  
  1. FOM = floor of mouth; BM = buccal mucosa; RMT = retromolar trigone; CRT = chemotherapy and/or radiotherapy; χ2 test and Fisher’s exact test was used