| |
PTHrP positive
|
PTHrP negative
|
χ2
|
P value
|
|---|
|
No. (%)
|
No. (%)
|
|---|
|
Age
| | | | |
|
≤55
|
146 (53.9 %)
|
121 (53.5 %)
|
0.006
|
0.941
|
|
>55
|
125 (46.1 %)
|
105 (46.5 %)
| | |
|
Tumor size
| | | | |
|
≤2 cm
|
133 (49.1 %)
|
145 (64.2 %)
|
11.372
|
0.001
|
|
>2 cm
|
138 (50.9 %)
|
81 (35.8 %)
| | |
|
Skin involvementa
| | | | |
|
No
|
223 (82.3 %)
|
196 (86.7 %)
|
1.834
|
0.176
|
|
Yes
|
48 (17.7 %)
|
30 (13.3 %)
| | |
|
LN metastasis
| | | | |
|
No
|
154 (57.7 %)
|
148 (67.6 %)
|
5.014
|
0.025
|
|
Yes
|
113 (42.3 %)
|
71 (32.4 %)
| | |
|
Unknown
|
4
|
7
| | |
|
Histologic grade
| | | | |
|
≤II
|
187 (70.8 %)
|
165 (74.7 %)
|
0.885
|
0.347
|
|
>II
|
77 (29.2 %)
|
56 (25.3 %)
| | |
|
Unknown
|
7
|
5
| | |
|
Clinical stage
| | | | |
|
I
|
95 (35.1 %)
|
100 (44.2 %)
|
6.937
|
0.031
|
|
II
|
116 (42.8 %)
|
94 (41.6 %)
| | |
|
III
|
60 (22.1 %)
|
32 (14.2 %)
| | |
|
ER
| | | | |
|
(−)
|
78 (29.2 %)
|
56 (26.9 %)
|
0.303
|
0.582
|
|
(+)
|
189 (70.8 %)
|
152 (73.1 %)
| | |
|
Unknown
|
4
|
18
| | |
|
HER-2
| | | | |
|
(−)
|
98 (40.3 %)
|
79 (39.7 %)
|
0.018
|
0.893
|
|
(+)
|
145 (59.7 %)
|
120 (60.3 %)
| | |
|
Unknown
|
28
|
27
| | |
|
Tumor type
| | | | |
|
IDCb
|
231 (85.2 %)
|
192 (85.0 %)
|
0.008
|
0.929
|
|
Non-IDCc
|
40 (14.8 %)
|
34 (15.0 %)
| | |
|
TGF-β
| | | | |
|
(−)
|
116 (42.8 %)
|
107 (47.3 %)
|
1.027
|
0.311
|
|
(+)
|
155 (57.2 %)
|
119 (52.7 %)
| | |
- askin involvement: edema, redness, nodularity, or ulceration
- bIDC, invasive ductal carcinoma
- cNon-IDC: invasive lobular carcinoma, mucinous or colloid carcinoma, medullary carcinoma, metaplastic carcinoma
