| |
TGF-β positive No. (%)
|
TGF-β negative No. (%)
|
χ2
|
P value
|
|---|
|
Age
| | | | |
|
≤55
|
156 (56.9 %)
|
111 (49.8 %)
|
2.534
|
0.111
|
|
>55
|
118 (43.1 %)
|
112 (50.2 %)
| | |
|
Tumor size
| | | | |
|
≤2 cm
|
137 (50.0 %)
|
141 (63.2 %)
|
8.729
|
0.003
|
|
>2 cm
|
137 (50.0 %)
|
82 (36.8 %)
| | |
|
Skin involvementa
| | | | |
|
No
|
229 (83.6 %)
|
190 (85.2 %)
|
0.245
|
0.620
|
|
Yes
|
45 (16.4 %)
|
33 (14.8 %)
| | |
|
LN metastasis
| | | | |
|
No
|
154 (57.5 %)
|
148 (67.9 %)
|
5.556
|
0.018
|
|
Yes
|
114 (42.5 %)
|
70 (32.1 %)
| | |
|
Unknown
|
6
|
5
| | |
|
Histologic grade
| | | | |
|
≤II
|
182 (67.7 %)
|
169 (78.2 %)
|
6.710
|
0.01
|
|
>II
|
87 (32.3 %)
|
47 (21.8 %)
| | |
|
Unknown
|
5
|
7
| | |
|
Clinical stage
| | | | |
|
I
|
91 (33.2 %)
|
104 (46.6 %)
|
9.329
|
0.009
|
|
II
|
128 (46.7 %)
|
82 (36.8 %)
| | |
|
III
|
55 (20.1 %)
|
37 (16.6 %)
| | |
|
ER
| | | | |
|
(−)
|
75 (28.7 %)
|
59 (27.6 %)
|
0.079
|
0.779
|
|
(+)
|
186 (71.3 %)
|
155 (72.4 %)
| | |
|
Unknown
|
13
|
9
| | |
|
HER-2
| | | | |
|
(−)
|
94 (38.7 %)
|
83 (41.7 %)
|
0.417
|
0.518
|
|
(+)
|
149 (61.3 %)
|
116 (58.3 %)
| | |
|
Unknown
|
31
|
24
| | |
|
Tumor type
| | | | |
|
IDCb
|
234 (85.4 %)
|
189 (84.8 %)
|
0.041
|
0.840
|
|
Non-IDCc
|
40 (14.6 %)
|
34 (15.2 %)
| | |
- askin involvement: edema, redness, nodularity, or ulceration
- bIDC, invasive ductal carcinoma
- cNon-IDC: invasive lobular carcinoma, mucinous or colloid carcinoma, medullary carcinoma, metaplastic carcinoma
