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Table 2 Description of MAX-negative cases

From: Somatic loss of function mutations in neurofibromin 1 and MYC associated factor X genes identified by exome-wide sequencing in a wild-type GIST case

Case

H-scorea

Age/Sex

Genotype

Riskb

Site

1

0.0

71/M

PDGRA exon 18

H

Gastric

2

3.2

48/F

KIT exon 11

H

Gastric

3

5.0

83/M

KIT exon 11

I

Gastric

4

5.9

39/M

KIT exon 11

L

Gastric

5

7.4

35/M

KIT exon 11

H

Other

6

10.9

n/ac

KIT exon 11

H

n/ac

7

13.6

46/M

KIT exon 11

I

Gastric

8

13.9

68/F

KIT exon 11, 17

H

Small bowel

9

14.2

72/M

KIT exon 11

I

Gastric

10

17.6

50/M

KIT exon 11

I

Gastric

  1. aH-score: nuclear staining intensity x percentage; bGIST prognosis based on tumor site, size, mitotic index. H= high, I = intermediate, L = low; cNot available