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Fig. 1 | BMC Cancer

Fig. 1

From: Somatic loss of function mutations in neurofibromin 1 and MYC associated factor X genes identified by exome-wide sequencing in a wild-type GIST case

Fig. 1

a WES (top) and Sanger (bottom) sequencing showing the two-base (TT) insertion in NF1. A subset of reads visualized on the Integrative Genomics Viewer (IGV) shows the insertion represented by the purple bar in 100 % of the tumor reads, as confirmed by the chromatogram below. b Top and bottom panels show the single-base (c) deletion in the MAX gene in a majority (~90 %) of reads, again confirmed by the chromatogram below. Red arrow indicates direction of transcription for MAX

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