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Fig. 6 | BMC Cancer

Fig. 6

From: Downregulation of toll-like receptor 4 induces suppressive effects on hepatitis B virus-related hepatocellular carcinoma via ERK1/2 signaling

Fig. 6

Structural and functional interaction of TLR4 and HBx in HepG2.2.15. a Immunofluorescence analysis revealed that TLR4 displayed a diffuse spotty distribution in the cytoplasm in HepG2.2.15 cells, and HBx had a similar cytoplasmic staining. b Lysates of HepG2.2.15 cells were immunoprecipitated with anti-HBx antibody and TLR4 protein was examined using Western blot analysis. TLR4 was detected in the immunoprecipitated HBx complex, but not in the IgG control sample. P < 0.05

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