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Fig. 3 | BMC Cancer

Fig. 3

From: Breast cancer metastasis suppressor 1 (BRMS1) attenuates TGF-β1-induced breast cancer cell aggressiveness through downregulating HIF-1α expression

Fig. 3

HIF-1α is important for TGF-β1-induced Snail expression. a The cells were transfected with indicated siRNAs and then stimulated with or without TGF-β1 (5 ng/ml) for 6 h. Immunoblotting. b The cells were transfected with indicated siRNAs and in vitro invasion was analyzed against TGF-β1 (5 ng/ml) (**P < 0.01 and ***P < 0.001 vs control scrambled siRNA, ###P < 0.001 vs control scrambled siRNA with TGF-β1). Representative results were presented from at least three independent experiments with similar results

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