| All women (N = 195) | Proliferative diagnosis1 (N = 141) | Non-proliferative diagnosis2 (N = 54) | P-heterogeneity¥ | |||
---|---|---|---|---|---|---|---|
Characteristics | Mean LTL§ | (95 % CI) § | Mean LTL§ | (95 % CI) § | Mean LTL§ | (95 % CI) § |  |
Age (years) | Â | Â | Â | Â | Â | Â | 0.817 |
  < 45 | 1.27 | (1.05, 1.55) | 1.47 | (1.13, 1.91) | 1.07 | (0.80, 1.42) |  |
 45–49 | 1.35 | (1.14, 1.60) | 1.47 | (1.20, 1.80) | 1.10 | (0.81, 1.50) |  |
 50–54 | 1.39 | (1.17, 1.64) | 1.46 | (1.21, 1.77) | 1.16 | (0.82, 1.64) |  |
  ≥ 55 | 1.23 | (1.04, 1.45) | 1.31 | (1.09, 1.58) | 0.94 | (0.65, 1.37) |  |
 P-trend | 0.774 | 0.423 | 0.745 |  | |||
Body mass index (Kg/m2) | Â | Â | Â | Â | Â | Â | 0.194 |
  < 25.0 | 1.24 | (1.10, 1.39) | 1.35 | (1.18, 1.55) | 0.93 | (0.73, 1.17) |  |
 25.0–29.9 | 1.29 | (1.09, 1.52) | 1.44 | (1.17, 1.78) | 1.09 | (0.83, 1.42) |  |
  ≥ 30 | 1.56 | (1.29, 1.90) | 1.57 | (1.26, 1.96) | 1.56 | (1.05, 2.31) |  |
 P-trend | 0.058 | 0.248 | 0.030 |  | |||
Age at menarche (years) | Â | Â | Â | Â | Â | Â | 0.743 |
  ≤ 12 | 1.26 | (1.09, 1.45) | 1.33 | (1.13, 1.57) | 1.01 | (0.74, 1.37) |  |
 13 | 1.36 | (1.17, 1.58) | 1.53 | (1.28, 1.83) | 1.08 | (0.83, 1.41) |  |
  ≥ 14 | 1.33 | (1.11, 1.58) | 1.43 | (1.17, 1.75) | 1.08 | (0.76, 1.53) |  |
 P-trend | 0.613 | 0.530 | 0.787 |  | |||
Parity | Â | Â | Â | Â | Â | Â | 0.739 |
 Parous | 1.30 | (1.17, 1.43) | 1.39 | (1.24, 1.55) | 1.07 | (0.88, 1.30) |  |
 Nulliparous | 1.35 | (1.14, 1.61) | 1.53 | (1.23, 1.89) | 1.08 | (0.81, 1.44) |  |
Age at first birth (years)* | Â | Â | Â | Â | Â | Â | 0.744 |
  < 30 | 1.21 | (1.08, 1.37) | 1.30 | (1.13, 1.50) | 1.00 | (0.79, 1.26) |  |
  ≥ 30 | 1.51 | (1.24, 1.83) | 1.66 | (1.31, 2.10) | 1.28 | (0.90, 1.81) |  |
 P-trend | 0.066 | 0.084 | 0.246 |  | |||
Menopausal status | Â | Â | Â | Â | Â | Â | 0.361 |
 Premenopausal | 1.37 | (1.19, 1.57) | 1.40 | (1.18, 1.66) | 1.22 | (0.98, 1.51) |  |
 Postmenopausal | 1.21 | (0.98, 1.50) | 1.45 | (1.15, 1.82) | 0.74 | (0.47, 1.17) |  |
Age at menopause (years) | Â | Â | Â | Â | Â | Â | 0.221 |
  < 45 | 1.37 | (1.03, 1.84) | 1.79 | (1.30, 2.46) | 0.67 | (0.39, 1.17) |  |
 45–49 | 1.19 | (0.94, 1.52) | 1.28 | (0.99, 1.66) | 1.18 | (0.68, 2.05) |  |
  ≥ 50 | 1.24 | (1.04, 1.48) | 1.31 | (1.09, 1.58) | 0.80 | (0.52, 1.22) |  |
 P-trend | 0.655 | 0.166 | 0.654 |  | |||
Menopausal hormone therapy use‡ |  |  |  |  |  |  | 0.461 |
 Never | 1.13 | (0.95, 1.35) | 1.26 | (1.02, 1.57) | 0.89 | (0.60, 1.34) |  |
 Ever | 1.49 | (1.22, 1.80) | 1.50 | (1.23, 1.84) | 1.10 | (0.60, 2.01) |  |
First degree family history of breast cancer | Â | Â | Â | Â | Â | Â | 0.883 |
 No | 1.25 | (1.13, 1.38) | 1.35 | (1.20, 1.51) | 1.03 | (0.85, 1.25) |  |
 Yes | 1.50 | (1.27, 1.78) | 1.64 | (1.34, 2.00) | 1.19 | (0.87, 1.61) |  |