Fig. 2
From: Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer
Representative MS/MS spectra of overexpressed proteins and validation of MIF by immunohistochemistry. Representative MS/MS spectra of overexpressed proteins in invasive GBC cell lines, OCUG-1, NOZ and GB-d1 as compared with the non-invasive GBC cell line, TGBC24TKB. a Macrophage migration inhibitory factor (MIF). b CD74 molecule, major histocompatibility complex, class II invariant chain (CD74). c CD44 antigen (CD44). d Validation of MIF by IHC. Representative sections from cholecystitis tissues (weak staining) – (i) stained with hematoxylin and eosin; (ii) probed with anti-MIF antibody. Representative sections from gallbladder adenocarcinoma tissue (strong staining) - (iii) stained with hematoxylin and eosin; (iv) probed with anti-MIF antibody