Fig. 9
From: Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines
Effect of TAM, 3-BP and their combination on the protein level of the Metastasis markers. The results of zymography and qPCR were confirmed also by western technique for MMP-2 and 9 in the cells of MCF-7 (a, c) and T47D (b, d). Results are expressed as means ± SD of 2 independent experiments western. The analysis was done by image software. Significance was determined with one way ANOVA using Tukey’s multiple comparison test.“a” Significantly different from control, “b” from 3-BP and “c” from TAM at P ≤ 0.05. ♦Significant interaction (antagonism) when TAM and 3-BP where combined using factorial design