Fig. 7
From: Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines
Effect of TAM, 3-BP and their combination on the level Hexokinaes-2 (HK-2). HK-2 gene expression of 3-BP, TAM and the combination regimen (a, b). The effect of different treatments on the HK-2 protein level. (c, d). Results are expressed as means ± SD of 2 independent experiments performed in duplicates for qPCR experiment and for western blot the results are expressed as means ± SD of 3 independent experiments. Significance was done by one way ANOVA using Tukey’s multiple comparison test. “a” Significantly different from control, “b” from 3-BP and “c” from TAM at P ≤ 0.05. ♦ means synergistic and * potentiation interaction when TAM and 3-BP where combined using factorial design