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Fig. 3 | BMC Cancer

Fig. 3

From: Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines

Fig. 3

Oxidative stress markers following treatment with TAM, 3-BP and their combination. Effect of different regimen on lipid peroxidation in MCF-7 (a) and T47D (b). Figure (c) and (d) show the content of reduced glutathione (rGSH) in MCF-7 and T47D, respectively after 48 h treatment with 3-BP, TAM and their combination. Results are expressed as means ± SD of 2 independent experiments performed in duplicates. Statistical significance of results was analyzed by one way ANOVA using Tukey’s multiple comparison test. “a” Significantly different from control, “b” from 3-BP and “c” from TAM at P ≤ 0.05. means synergistic and * means potentiating interaction when TAM and 3-BP where combined using factorial design

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