Fig. 12
From: Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines
VEGF expression using immunohistochemsitry. a: Paraffin section photograph of mouse solid tumor (control group) showing the increased VEGF expression in most tumor cells, the large capillaries and hyperchromatic cells were present (4/5 of the field). b: Paraffin section photograph of mouse solid tumor (group treated with 10Â mg/kg3-BP) showing the VEGF expression in most tumor cells absent the apoptotic cells (3/5 of the field). c: Paraffin section photograph of mouse solid tumor (group treated with 5Â mg/kg) showing the VEGF expression in some tumor cells, absent in mitotic and apoptotic cell, large conjugated blood vessels were observed. (1/5 of the field). d: Paraffin section photograph of mouse solid tumor (group treated with 3-BP and TAM) showing the VEGF expression in some tumor cells (1/5 of the field)