Fig. 10
From: Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines
Tumor volume of solid Erlich carcinoma-bearing mice after treatment with 3-BP, TAM or their combination. The tumor volume was markedly reduced in mice treated 3-BP (10 mg/kg), TAM (5 mg/kg); however the best result was observed in group treated with combination of both drugs. Results are expressed as means ± SD of tumor volume from 6 mice. Results are analyzed by one way ANOVA using Tukey’s multiple comparison test. “a” Significantly different from control,“b” from 3-BP and “c” from TAM at P < 0.05. ♦Significant interaction when TAM and 3-BP where combined using factorial design