| |
Adjusted OR (95 % CI) any fracturea
|
Adjusted OR (95 % CI) accidental fracturea
|
Adjusted OR (95 % CI) hip fracturea
|
|---|
|
No ADT
|
1.0 (Reference)
|
1.0 (Reference)
|
1.0 (Reference)
|
|
GnRH agonists + anti-androgens
|
3.48 (3.07–3.96)
|
1.60 (1.36–1.88)
|
1.82 (1.39–2.38)
|
|
GnRH agonist only
|
1.33 (1.09–1.63)
|
1.17 (0.93–1.47)
|
1.70 (1.19–2.42)
|
|
Anti-androgen only
|
2.11 (1.72–2.59)
|
1.37 (1.07–1.77)
|
1.81 (1.24–2.63)
|
|
Orchiectomy alone
|
2.54 (1.76–3.66)
|
2.18 (1.43–3.33)
|
1.88 (0.96–3.67)
|
|
Orchiectomy + pharmacologic ADT
|
4.32 (3.34–5.58)
|
1.39 (0.93–2.07)
|
1.59 (0.86–2.93)
|
- ADT androgen deprivation therapy, GnRH gonadotropin-releasing hormone, OR odds ratio, CI confidence interval
- aAdjusted for age at diagnosis and ethnicity
- Bold indicate significant p-value (<0.5)
