Table 5 Risk of fracture associated with ADT by extent of disease and age
Adjusted OR (95 % CI) any fracture | Adjusted OR (95 % CI) accidental fracture | Adjusted OR (95 % CI) hip fracture | |
|---|---|---|---|
ADT a | |||
No | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) |
Yes | 2.83 (2.52–3.17) | 1.47 (1.28–1.68) | 1.82 (1.44–2.30) |
Extent of disease a | |||
Localised | |||
No ADT | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) |
ADT | 3.42 (1.70–6.88) | 1.85 (0.72–4.74) | 6.56 (1.32–32.64) |
Locally advanced or Metastatic | |||
No ADT | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) |
ADT | 3.73 (2.83–4.91) | 1.38 (0.94–2.05) | 3.43 (1.44–8.19) |
Unknown | |||
No ADT | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) |
ADT | 2.21 (1.93–2.52) | 1.40 (1.20–1.63) | 1.60 (1.25–2.06) |
Age b | |||
< 65 | |||
No ADT | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) |
ADT | 4.67 (3.76–5.81) | 1.50 (1.10–2.05) | 2.02 (0.93–4.39) |
≥ 65 | |||
No ADT | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) |
ADT | 2.89 (2.55–3.29) | 1.87 (1.61–2.17) | 2.53 (1.99–3.22) |