Reprogramming energy metabolism and inducing angiogenesis: co-expression of monocarboxylate transporters with VEGF family members in cervical adenocarcinomas

Table 6 Associations of the metabolism-related proteins with the VEGF family members

	VEGF-A			VEGF-C			VEGF-D			VEGFR-1			VEGFR-2			VEGFR-3
	n	Positive (%)	p	n	Positive (%)	p	n	Positive (%)	p	n	Positive (%)	p	n	Positive (%)	p	n	Positive (%)	p
MCT1			0.320			0.010			0.958			0.916			0.311			0.686
Negative	61	37 (60.7)		64	53 (82.8)		60	35 (58.3)		57	16 (28.1)		59	54 (91.5)		60	39 (65.0)
Positive	95	65 (68.4)		96	92 (95.8)		97	57 (58.8)		97	28 (28.9)		93	89 (95.7)		88	60 (68.2)
MCT4			0.037			0.699			0.878			0.319			0.359			0.026
Negative	21	9 (42.9)		22	21 (95.5)		22	13 (59.1)		22	8 (36.4)		22	22 (100.0)		21	9 (42.9)
Positive	137	91 (66.4)		140	125 (89.3)		136	78 (57.4)		134	35 (26.1)		134	124 (92.5)		128	87 (68.0)
CD147			0.138			0.122			0.074			0.187			1.000			0.223
Negative	146	91 (62.3)		149	136 (91.3)		147	82 (55.8)		145	39 (26.9)		143	134 (93.7)		138	89 (64.5)
Positive	13	11 (84.6)		13	10 (76.9)		12	10 (83.3)		11	5 (45.5)		11	11 (100.0)		12	10 (83.)
GLUT1			0.718			0.115			0.475			0.387			0.811			0.196
Negative	81	51 (63.0)		83	71 (85.5)		80	43 (53.8)		81	20 (24.7)		81	76 (93.8)		74	46 (62.2)
Positive	73	48 (65.8)		75	70 (93.3)		74	44 (59.5)		71	22 (31.0)		70	65 (92.9)		72	52 (72.2)
CAIX			0.876			0.740			0.135			0.982			0.818			0.149
Negative	25	16 (64.0)		26	24 (92.3)		25	11 (44.0)		25	7 (28.0)		26	24 (92.3)		26	14 (53.8)
Positive	128	84 (65.6)		131	116 (88.5)		128	77 (60.2)		126	35 (27.8)		124	116 (93.5)		118	81 (68.6)

ISSN: 1471-2407