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Table 5 Univariate Cox proportional hazard regression analysis for time to biochemical progression according to tumor expression of IAPs and caspases

From: Prognostic value of inhibitors of apoptosis proteins (IAPs) and caspases in prostate cancer: caspase-3 forms and XIAP predict biochemical progression after radical prostatectomy

  p HR (95 % CI)   p HR (95 % CI)
cIAP1/2 0.931 0.970 (0.485-1.938) Procaspase-8 0.962 1.018 (0.487-2.129)
cIAP2 0.646 1.176 (0.588-2.351) Cleaved caspase-8 0.222 0.653 (0.330-1.294)
NAIP 0.543 0.811 (0.412-1.596) Procaspase-3 0.005* 0.260 (0.100-0.672)
Survivin 0.108 1.831 (0.875-3.834) Cleaved caspase-3 0.002* 0.327 (0.161-0.662)
XIAP 0.055 0.460 (0.208-1.016) Caspase-7 0.435 1.310 (0.665-2.579)
    Procaspase-9 0.936 1.029 (0.515-2.055)
  1. Abbreviations: CI confidence interval, HR hazard ratio. Bold values indicate statistical significance. *p < 0.05