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Table 3 Correlation between tumor expression of IAPs and caspases and clinicopahological features

From: Prognostic value of inhibitors of apoptosis proteins (IAPs) and caspases in prostate cancer: caspase-3 forms and XIAP predict biochemical progression after radical prostatectomy

  cIAP1/2 cIAP2 NAIP Survivin XIAP
  r p r p r p r p r p
Preoperative serum PSA −0.066 0.549 −0.017 0.877 0.069 0.531 0.185 0.091 −0.025 0.228
Pathological T stage 0.219 0.045* 0.019 0.866 0.037 0.735 0.101 0.362 −0.136 0.218
Clinical T stage 0.103 0.349 0.034 0.759 0.118 0.287 0.090 0.414 0.089 0.419
Gleason score 0.153 0.165 −0.124 0.262 0.052 0.641 −0.172 0.118 0.084 0.446
Perineural invasion 0.110 0.320 0.066 0.551 0.079 0.476 0.229 0.036* −0.088 0.426
Node involvement 0.122 0.267 0.000 1.000 0.047 0.672 −0.025 0.824 0.030 0.455
Positive surgical margins 0.066 0.549 0.222 0.042* 0.127 0.251 0.055 0.619 −0.179 0.109
Biochemical progresion −0.002 0.983 0.086 0.438 −0.041 0.711 0.188 0.086 −0.210 0.056
Survival −0.090 0.414 −0.077 0.489 0.119 0.281 0.239 0.019* −0.331 0.002*
  1. Correlations between immunohistochemical variables (according to the stratification shown in Table 2) and preoperative serum PSA, pathological T stage, clinical T stage and Gleason score were evaluated by Spearman’s test (r, correlation coefficient). *p < 0.05. (Note: significant correlations after Bonferroni correction should be those with a p < 0.005)