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Fig. 10 | BMC Cancer

Fig. 10

From: Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and angiogenesis

Fig. 10

Effect of long term culturing HMEC spheres in OPG rich medium on the copy number of genes relevant to oncogenic pathways. a Schematic of culturing three generations of HMEC spheres in presence of rhOPG. b Copy number differences among HMEC, SUM149PT, and SUM1315MO2 adherent cells. c Copy number differences among HMEC, SUM149PT, and SUM1315MO2 spheres. d Comparison of copy number analysis of reference and inflammatory breast cancer tissue DNA. e Comparison of copy number analysis of HMEC spheres cultured for three generations in the absence or presence of 500 pg/ml rhOPG

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