Factor | 5-year OS rate (%) (95Â % CI) | UA (p value) | MA (p value) |
---|---|---|---|
Age at radiotherapy | Â | 0.393 | 0.162 |
 66 years or less | 47.2 (38.7–55.9) |  |  |
 More than 66 years | 39.4 (30.5–49.1) |  |  |
Gender | Â | 0.100 | 0.215 |
 Male | 41.2 (34.6–48.1) |  |  |
 Female | 58.1 (40.8–73.7) |  |  |
Performance status | Â | 0.008 | 0.655 |
 0 | 48.7 (33.1–64.6) |  |  |
 1 | 44.3 (36.7–52.1) |  |  |
 2 | 22.3 (9.5–44.1) |  |  |
Primary site | Â | 0.714 | 0.810 |
 Upper thoracic esophagus | 38.9 (24.4–55.7) |  |  |
 Middle thoracic esophagus | 42.9 (34.4–51.9) |  |  |
 Lower thoracic esophagus | 46.6 (35.7–57.8) |  |  |
Stage | Â | <0.001 | <0.001 |
 II | 64.0 (52.5–74.2) |  |  |
 III (non-T4) | 40.1 (31.0–49.9) |  |  |
 III (T4) | 22.5 (13.7–35.5) |  |  |
Protocol | Â | 0.082 | 0.043 |
 Group A | 52.4 (35.0–69.3) |  |  |
 Group B | 45.2 (37.0–53.6) |  |  |
 Group C | 37.2 (26.8–48.8) |  |  |
Radiotherapy dose | Â | 0.090 | 0.973 |
 60 Gy or less | 46.0 (28.1–51.2) |  |  |
 More than 60 Gy | 39.1 (38.7–53.5) |  |  |
Concomitant chemotherapy | Â | <0.001 | <0.001 |
 1 cycle | 27.9 (14.5–46.9) |  |  |
 2 cycles | 46.0 (39.3–52.8) |  |  |
Adjuvant chemotherapy | Â | 0.885 | 0.306 |
 With | 45.1 (38.1–52.5) |  |  |
 Without | 38.8 (26.8–52.3) |  |  |