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Table 1 Benzofuroxan compounds and derivatives

From: Benzofuroxan derivatives N-Br and N-I induce intrinsic apoptosis in melanoma cells by regulating AKT/BIM signaling and display anti metastatic activity in vivo

Compound

R1

R2

R3

Compound

R1

R2

R3

1

H

H

H

13

N(CH3)2

H

H

2

CH3

H

H

14

n-C4H9

H

H

3

NH2

H

H

15

tert-C4H9

H

H

4

OH

H

H

16

OC3H7

H

H

5

F

H

H

17

Cl

H

Cl

6

CN

H

H

18

Cl

Cl

H

7

CH2CH3

H

H

19

CF3

H

H

8

OCH3

H

H

20

OC4H9

H

H

9

Cl

H

H

21

Br

H

H

10

COCH3

H

H

22

SO2NH2

H

H

11

n-C3H7

H

H

23

I

H

H

12

Iso-C3H7

H

H

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