Fig. 5From: Benzofuroxan derivatives N-Br and N-I induce intrinsic apoptosis in melanoma cells by regulating AKT/BIM signaling and display anti metastatic activity in vivoExpression of p-AKT and BIM in B16F10-Nex2 cells treated with N-I and N-Br, assessed by Western blotting. B16F10-Nex2 were treated with both compounds at IC50 for 6Â h in presence or absence of NAC. Î’-actin was used as loading controlBack to article page