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Table 3 Impact of KITL541, tumor size, location, mitotic index and mutational status on RFS at 5 years in multivariate analysis

From: KIT exon 10 variant (c.1621 A > C) single nucleotide polymorphism as predictor of GIST patient outcome

Variable

HR (95 % CI)

P

KIT L541

6.1 (1.8–21)

0.004

Tumor size (<50 mm versus ≥ 50 mm)

3.6 (1.1–12)

0.03

Location (gastric versus non gastric)

0.5 (0.1–2)

0.06

Mitotic index per 50 HPF (<5 versus ≥5)

6.2 (1.7–23)

0.006

Mutation status (all other versus KIT exon 11)

1.5 (0.4–5)

0.6

  1. HR Hazard ratio, CI confidence intervals