Table 2 Survival outcomes for the surrogate endpoints at 2 and 3 years
Surrogate endpoint | Events | Survival rates a | ||||
|---|---|---|---|---|---|---|
NACT+CCRT group | CCRT group | Total, | NACT+CCRT group, % | CCRT group, % | P-value * | |
(n = 104, %) | (n = 104, %) | No. (%) | ||||
At 2 years | ||||||
PFS | 15 (14.4) | 25 (24.0) | 40 (29.2) | 87 | 76 | 0.078 |
FFS | 14 (13.5) | 22 (21.2) | 36 (27.3) | 87 | 79 | 0.134 |
D-FFS | 12 (11.5) | 21 (20.2) | 33 (15.9) | 88 | 80 | 0.092 |
LR-FFS | 3 (2.9) | 6 (5.8) | 9 (4.3) | 98 | 94 | 0.284 |
At 3 years | ||||||
PFS | 19 (18.3) | 31 (29.8) | 50 (24.0) | 83 | 72 | 0.049 |
FFS | 16 (15.4) | 28 (26.9) | 44 (21.2) | 85 | 75 | 0.040 |
D-FFS | 12 (11.5) | 25 (24.0) | 37 (17.8) | 88 | 77 | 0.022 |
LR-FFS | 5 (4.8) | 9 (8.7) | 14 (6.7) | 95 | 92 | 0.235 |