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Fig. 5 | BMC Cancer

Fig. 5

From: Incarvine C suppresses proliferation and vasculogenic mimicry of hepatocellular carcinoma cells via targeting ROCK inhibition

Fig. 5

Inhibitory effect of IVC on MHCC97H cell motility. a Cells were plated, incubated for 8 h, scratched and treated with vehicle, IVC or Y27632. Representative images of scratch wounds formed at 0, 24 and 48 h after wounding. Original magnification was 100×, scale bars represent 125 μm. c MHCC97H cells were treated with vehicle, IVC or Y27632, plated in Corning Transwell inserts coated with Matrigel, and allowed to invade for 48 h. Original magnification was 200×, scale bars represent 75 μm. b and d Data were normalized to untreated cells and the relative migration or invasion is expressed as mean ± S.E. of triplicate experiments. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. the control

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