Fig. 8

BMP7 mediates KDM5C-induced migration and invasion in HCC cells. a Silenced BMP7 protein expression in MHCC97L-pSuper-shKDM5C cells was measured by Western blotting. b, Silenced BMP7 mRNA expression in MHCC97L-pSuper-shKDM5C cells was measured by qRT-PCR. c MHCC97L-pSuper-shKDM5C cells treated with siBMP7 were subjected to Transwell migration (top), and Matrigel invasion assays (bottom), quantification of migrated cells through the membrane and invaded cells through Matrigel of each cell line are shown as proportions of their vector controls. **, P < 0.01 is based on the Student t test. All results are from three independent experiments. Error bars, SD