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Table 2 Correlation of CD68-positiveTAMs in the tumor invasive front with clinicopathological characteristics of hilar cholangiocarcinoma

From: Prognostic significance of macrophage invasion in hilar cholangiocarcinoma

Clinicopathological analysis
Variable high CD68 low CD68 p
No. of patients 26 21  
Gender    0.552
 Male 13 (50 %) 10 (47.6 %)  
 Female 13 (50 %) 11 (52.4 %)  
Patient age, years    0.448
 ≤60 14 (53.8 %) 12 (47.6 %)  
 >60 12 (46.2 %) 11 (52.4 %)  
Histological differentiation    0.307
 Well/moderate 21 (80.8 %) 19 (90.5 %)  
 Poor 5 (19.2 %) 2 (9.5 %)  
Pathological T stage    0.413
 T2 8 (30.8 %) 8 (38.1 %)  
 T3 18 (67.9 %) 13 (61.9 %)  
Pathological N stage    0.307
 Negative 19 (73.1 %) 13 (61.9 %)  
 Positive 7 (26.9 %) 8 (38.1 %)  
Perineural sheath infiltration    0.390
 Negative 3 (11.5 %) 1 (4.8 %)  
 Positive 23 (88.5 %) 20 (95.2 %)  
Lymphangiosis carcinomatosa    0.576
 Negative 12 (46.2 %) 10 (47.6 %)  
 Positive 14 (53.8 %) 11 (52.4 %)  
Perivascular lymphangiosis    0.552
 Negative 13 (50 %) 11 (52.4 %)  
 Positive 13 (50 %) 10 (47.6 %)  
Vascular invasion    0.549
 Negative 18 (69.2 %) 14 (66.6 %)  
 Positive 8 (30.8 %) 7 (33.3 %)  
Tumor recurrence    0.015
 Without 8 (30.8 %) 14 (66.7 %)  
 With 18 (69.2 %) 7 (33.3 %)  
Local recurrence    0.001
 Without 9 (34.6 %) 18 (85.7 %)  
 With 17 (65.4 %) 3 (14.3 %)  
Distant metastases    0.390
 Without 19 (73.1 %) 17 (81.7 %)  
 With 7 (26.9 %) 4 (19.0 %)