Table 2 Correlation of CD68-positiveTAMs in the tumor invasive front with clinicopathological characteristics of hilar cholangiocarcinoma
From: Prognostic significance of macrophage invasion in hilar cholangiocarcinoma
Clinicopathological analysis | ᅟ | ᅟ | ᅟ |
|---|---|---|---|
Variable | high CD68 | low CD68 | p |
No. of patients | 26 | 21 | |
Gender | 0.552 | ||
Male | 13 (50 %) | 10 (47.6 %) | |
Female | 13 (50 %) | 11 (52.4 %) | |
Patient age, years | 0.448 | ||
≤60 | 14 (53.8 %) | 12 (47.6 %) | |
>60 | 12 (46.2 %) | 11 (52.4 %) | |
Histological differentiation | 0.307 | ||
Well/moderate | 21 (80.8 %) | 19 (90.5 %) | |
Poor | 5 (19.2 %) | 2 (9.5 %) | |
Pathological T stage | 0.413 | ||
T2 | 8 (30.8 %) | 8 (38.1 %) | |
T3 | 18 (67.9 %) | 13 (61.9 %) | |
Pathological N stage | 0.307 | ||
Negative | 19 (73.1 %) | 13 (61.9 %) | |
Positive | 7 (26.9 %) | 8 (38.1 %) | |
Perineural sheath infiltration | 0.390 | ||
Negative | 3 (11.5 %) | 1 (4.8 %) | |
Positive | 23 (88.5 %) | 20 (95.2 %) | |
Lymphangiosis carcinomatosa | 0.576 | ||
Negative | 12 (46.2 %) | 10 (47.6 %) | |
Positive | 14 (53.8 %) | 11 (52.4 %) | |
Perivascular lymphangiosis | 0.552 | ||
Negative | 13 (50 %) | 11 (52.4 %) | |
Positive | 13 (50 %) | 10 (47.6 %) | |
Vascular invasion | 0.549 | ||
Negative | 18 (69.2 %) | 14 (66.6 %) | |
Positive | 8 (30.8 %) | 7 (33.3 %) | |
Tumor recurrence | 0.015 | ||
Without | 8 (30.8 %) | 14 (66.7 %) | |
With | 18 (69.2 %) | 7 (33.3 %) | |
Local recurrence | 0.001 | ||
Without | 9 (34.6 %) | 18 (85.7 %) | |
With | 17 (65.4 %) | 3 (14.3 %) | |
Distant metastases | 0.390 | ||
Without | 19 (73.1 %) | 17 (81.7 %) | |
With | 7 (26.9 %) | 4 (19.0 %) |