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Fig. 3 | BMC Cancer

Fig. 3

From: Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compounds

Fig. 3

SINE compound-mediated effects on protein expression in HT1080 parental versus resistant cells show differential dose–response. Parental and resistant cells were treated with 0, 0.03, 0.1, 0.6, 1, and 3 μM KPT-185 for 24 hours and then evaluated by immunoblot analysis for the expression of XPO1, p53, p21, full-length (FL) and cleaved (Cl) PARP, full-length and cleaved Caspase 3, Mcl-1, p-pRb, pRb, and actin

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BMC Cancer

ISSN: 1471-2407

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