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Table 6 The difference between normalizers

From: Small nucleolar RNA U91 is a new internal control for accurate microRNAs quantification in pancreatic cancer

miRNAs

Internal controls

U6

miR-16

U91

U6 + U91

miR-21

2.97E-06; p< 0.001

0.003404; p< 0.01

0.7979; p > 0.05

0.000789; p< 0.01

miR-96

0.003078; p< 0.01

0.02723; p< 0.05

0.639203; p > 0.05

0.038631; p< 0.05

miR-148a

4.66E-06; p< 0.001

0.007849; p< 0.01

0.3078; p > 0.05

0.000586; p< 0.01

miR-155

6.13E-05; p< 0.01

0.000873; p< 0.01

0.534202; p > 0.05

0.001831; p< 0.01

miR-196a

7.93E-07; p< 0.001

0.042034; p< 0.05

0.862491; p > 0.05

0.000117; p< 0.01

miR-217

0.003951; p< 0.01

0.065696; p > 0.05

0.024668; p< 0.05

0.008373; p< 0.05

  1. MicroRNA expression levels were normalized relative to the alien spike, in comparison with the normalizations relative to other internal controls. Data are presented as P-values of the paired Student’s t-test. p < 0.05 was considered statistically significant. P-values for the statistically significant differences are shown in bold